MBC BioLabs
953 Indiana St., San Francisco, CA 94107
OUR DISCOVERY
targeting chromatin networks
There is a necessity for new types of treatments in chromatin driven diseases like pediatric diffuse midline glioma (DMG).
TippingPoint has found a way to recapitulate the disease driving chromatin interactions in a test tube and uniquely target these aberrant interactions in disease.
OUR MISSION & VISION
TippingPoint Biosciences' mission is to treat diseases caused by dysfunctional genome chromatin packaging that are difficult to target using conventional approaches.
Chromatin structure dictates cell function and identity.
OUR SOLUTION
Team & advisory
Open positions
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NEWS & PRESS RELEASES
Stay informed to empower yourself with the latest knowledge and insights.
December 12, 2023
Astellas received more than 25 applications for the prize. After careful consideration and a competitive pitch process, both companies were chosen for strength of the innovation in their approach, the therapeutic potential of their research and expandability of their technological platforms.
January 7, 2023
A wide number of cancers exhibit misregulated genome packaging at the chromatin level. If chromatin that should be tightly condensed, becomes loosely packed (or vice-versa), the normal brakes on cell growth aren’t operant, leading to uncontrolled cell growth. Being able to regulate and control the chromatin state has been a high-value target for oncology.
October 17, 2023
More than 30 startups — including 18 from the Bay Area — pitched to investors at an event leading up to the Biotechnology Innovation Organization's Investor Forum on Tuesday and Wednesday.
September 15, 2023
We talked with the founder of TippingPoint Biosciences — Laura Hsieh, CEO — in the basement of IndieBio last week after her company had just been voted “Killer of the Week” by her peers in Batch 14. Each week at IndieBio, the companies in our batch compete based on their top accomplishments just in the previous week as they learn to move at venture speed. Top companies are nominated by the IndieBio SF team, but the winner is ultimately chosen by a voting of their peers within the batch.
November 9, 2023
Within each of the trillions of cells in our bodies, more than six feet of DNA is carefully packaged, encoding instructions for the biological processes we need to live. The secret to that precise packaging, which allows so much DNA to compress into the tiny space of a cell’s nucleus, lies in the power of the nucleosome.
December 12, 2023
Astellas received more than 25 applications for the prize. After careful consideration and a competitive pitch process, both companies were chosen for strength of the innovation in their approach, the therapeutic potential of their research and expandability of their technological platforms.
October 17, 2023
More than 30 startups — including 18 from the Bay Area — pitched to investors at an event leading up to the Biotechnology Innovation Organization's Investor Forum on Tuesday and Wednesday.
January 7, 2023
A wide number of cancers exhibit misregulated genome packaging at the chromatin level. If chromatin that should be tightly condensed, becomes loosely packed (or vice-versa), the normal brakes on cell growth aren’t operant, leading to uncontrolled cell growth. Being able to regulate and control the chromatin state has been a high-value target for oncology.
September 15, 2023
We talked with the founder of TippingPoint Biosciences — Laura Hsieh, CEO — in the basement of IndieBio last week after her company had just been voted “Killer of the Week” by her peers in Batch 14. Each week at IndieBio, the companies in our batch compete based on their top accomplishments just in the previous week as they learn to move at venture speed. Top companies are nominated by the IndieBio SF team, but the winner is ultimately chosen by a voting of their peers within the batch.
November 9, 2023
Within each of the trillions of cells in our bodies, more than six feet of DNA is carefully packaged, encoding instructions for the biological processes we need to live. The secret to that precise packaging, which allows so much DNA to compress into the tiny space of a cell’s nucleus, lies in the power of the nucleosome.